Collagen
Collagen is the most abundant structural protein in the human body, forming the framework of connective tissues, tendons, ligaments, blood vessels, cartilage and skin. Its integrity is fundamental to tissue structure, function and long-term health.
The effectiveness of a collagen supplement depends not simply on the amount of collagen consumed, but on the form in which it is delivered. Peptide composition, molecular weight and bioavailability all influence how efficiently collagen can be absorbed, transported and utilised within the body.
InnerCode’s Pure Tripeptide Collagen is built around an advanced collagen tripeptide technology containing over 80% tripeptides and an ultra-low molecular weight of just 500 Daltons. These highly specialised bioactive peptides are significantly smaller than those found in conventional hydrolysed collagen, enabling rapid absorption and delivering up to 5x greater bioavailability.
Bioavailability – Maximised Absorption
Twice absorbed. Fully delivered.
Cumulative absorption (AUC) over four hours — InnerCode Tripeptide Collagen reaches full systemic uptake while conventional collagens plateau below 50%.
InnerCode Tripeptide Collagen
100% absorption
Fully delivered within 4 hours
Collagen 2,000 Da
48% absorption
Less than half taken up
Collagen 5,000 Da
40% absorption
Weakest systemic uptake
Once absorbed, collagen tripeptides can enter circulation intact, allowing them to participate in biological processes beyond simple amino acid delivery. This has led to growing scientific interest in their potential role in tissue regeneration, cellular signalling and metabolic health.
Recent research conducted by the University of Milan investigated the same collagen tripeptide technology used in InnerCode’s formulation and demonstrated both DPP-IV inhibitory activity and GLP-1 stimulation in laboratory models. The study reported a 17% increase in GLP-1 secretion, highlighting the emerging biological activity of advanced collagen tripeptides and their potential relevance to metabolic health.
Molecular weight distribution
Lower. Tighter. Better engineered.
How InnerCode Tripeptide compares against conventional collagen and tripeptide — the only ingredient concentrated within the 300–500 Da bioactive range.
InnerCode Tripeptide Collagen
300-500 Da
Sharp, concentrated peak
Tripeptide Competitor
~1,200 Da
Broad, lower-purity profile
Conventional Collagen
2,000-3,000 Da
Wide spread, weak absorption
The exceptional absorption profile of Pure Tripeptide Collagen allows effective support with a daily serving up to 75% lower than many traditional collagen supplements, without compromising delivery of biologically relevant peptides.
By combining advanced tripeptide technology, ultra-low molecular weight and exceptional bioavailability, InnerCode’s Pure Tripeptide Collagen is designed to support connective tissue integrity, cardiovascular health, recovery, healthy ageing and overall wellbeing.
Collagen quality is defined by more than concentration alone. Peptide structure, molecular weight and bioavailability all play a critical role in determining how effectively collagen can support the body.
Peak Bioactivity
Why 300–500 Daltons?
Bioactivity peaks within a narrow molecular window — and InnerCode Tripeptide Collagen is engineered to land precisely inside it.
Maximum activity at 300–500 Da
Tripeptides at this molecular window deliver 100% of the measurable bioactivity peak.
Steep drop above 1,000 Da
Bioactivity falls to 60% by 1,000 Da and continues to decline as size increases.
Inactive above 5,000 Da
Conventional collagen peptides show effectively no bioactivity in this range.
Mechanism of Action
Two pathways. One coordinated effect.
Each pathway cascades from a measured biochemical effect into a targeted body-level benefit.
DPP-IV Inhibition
-47%
DPP-IV activity
Sustains GLP-1 activity
Improves the post-mealglucose response
GLP-1 Stimulation
+17%
GLP-1 secretion
Enhances incretin signaling
Promotes satiety and balanced glucosemetabolism
ACE Modulation
-48%
ACE activity
Supports vascular relaxation
Aids healthy bloodpressure and circulation
How It Works
A science-led range of precision-formulated supplements designed to support absorption, bioavailability and personalised wellness from the inside out.
Magnesium
A three-form magnesium blend that helps support muscle recovery, energy production, relaxation and nervous system balance.
Stress & Mood
A science-led blend of saffron, botanicals and magnesium designed to support calm, focus, emotional wellbeing and resilience to everyday stress.
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